ITGB3 monoclonal antibody, clone 3E8A6
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human ITGB3.
Immunogen
Recombinant protein corresponding to amino acids 27-179 of human ITGB3.
Host
Mouse
Theoretical MW (kDa)
87
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Flow Cytometry (1:200-1:400)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200-1:1000)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: ITGB3-hIgGFc transfected HEK293 cell lysates with ITGB3 monoclonal antibody, clone 3E8A6 (Cat # MAB21405).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human bladder carcinoma with ITGB3 monoclonal antibody, clone 3E8A6 (Cat # MAB21405).Enzyme-linked Immunoabsorbent Assay
ELISA analysis with ITGB3 monoclonal antibody, clone 3E8A6 (Cat # MAB21405).Flow Cytometry
Flow cytometric analysis of HL-60 cells with ITGB3 monoclonal antibody, clone 3E8A6 (Cat # MAB21405) (Green). Red: Negative Control. -
Gene Info — ITGB3
Entrez GeneID
3690Protein Accession#
P05106Gene Name
ITGB3
Gene Alias
CD61, GP3A, GPIIIa
Gene Description
integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
Omim ID
173470Gene Ontology
HyperlinkGene Summary
The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. [provided by RefSeq
Other Designations
integrin beta chain, beta 3|platelet glycoprotein IIIa
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Interactome
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