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Last updated: 2021/6/13

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FZD4 monoclonal antibody, clone 2F3A7 

  • Catalog # : MAB21396
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant human FZD4.
  • Immunogen:
  • Recombinant protein corresponding to amino acids 37-222 of human FZD4.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 60
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Recommend Usage:
  • ELISA (1:10000)
    Flow Cytometry (1:200-1:400)
    Western Blot (1:500-1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.05% sodium azide).
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western Blot analysis of Lane 1: HEK293 and Lane 2: FZD4-hIgGFc transfected HEK293 cell lysates with FZD4 monoclonal antibody, clone 2F3A7 (Cat # MAB21396).
  • Enzyme-linked Immunoabsorbent Assay
  • Enzyme-linked Immunoabsorbent Assay
  • ELISA analysis with FZD4 monoclonal antibody, clone 2F3A7 (Cat # MAB21396).
  • Flow Cytometry
  • Flow Cytometry
  • Flow cytometric analysis of HL-60 cells with FZD4 monoclonal antibody, clone 2F3A7 (Cat # MAB21396) (Green). Red: Negative Control.
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Enzyme-linked Immunoabsorbent Assay
  • Enzyme-linked Immunoabsorbent Assay
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 8322
  • Gene Name:
  • FZD4
  • Gene Alias:
  • CD344,EVR1,FEVR,FZD4S,Fz-4,FzE4,GPCR,MGC34390
  • Gene Description:
  • frizzled homolog 4 (Drosophila)
  • Gene Summary:
  • This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence. [provided by RefSeq
  • Other Designations:
  • WNT receptor frizzled-4,exudative vitreoretinopathy 1 (autosomal dominant; Criswick-Schepens syndrome),frizzled 4
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