LTBR monoclonal antibody, clone 1D1C5C8
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human LTBR.
Immunogen
Recombinant protein corresponding to amino acids 31-227 of human LTBR.
Host
Mouse
Theoretical MW (kDa)
46.7
Reactivity
Human
Form
Liquid
Isotype
IgG2a
Recommend Usage
ELISA (1:10000)
Flow Cytometry (1:200-1:400)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: LTBR-hIgGFc transfected HEK293 cell lysates with LTBR monoclonal antibody, clone 1D1C5C8 (Cat # MAB21393).Enzyme-linked Immunoabsorbent Assay
ELISA analysis with LTBR monoclonal antibody, clone 1D1C5C8 (Cat # MAB21393).Flow Cytometry
Flow cytometric analysis of HL-60 cells with LTBR monoclonal antibody, clone 1D1C5C8 (Cat # MAB21393) (Green). Red: Negative Control. -
Gene Info — LTBR
Entrez GeneID
4055Protein Accession#
P36941Gene Name
LTBR
Gene Alias
D12S370, LT-BETA-R, TNF-R-III, TNFCR, TNFR-RP, TNFR2-RP, TNFRSF3
Gene Description
lymphotoxin beta receptor (TNFR superfamily, member 3)
Omim ID
600979Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the tumor necrosis factor (TNF) family of receptors. It is expressed on the surface of most cell types, including cells of epithelial and myeloid lineages, but not on T and B lymphocytes. The protein specifically binds the lymphotoxin membrane form (a complex of lymphotoxin-alpha and lymphtoxin-beta). The encoded protein and its ligand play a role in the development and organization of lymphoid tissue and tranformed cells. Activation of the encoded protein can trigger apoptosis. [provided by RefSeq
Other Designations
TNFR superfamily, member 3|lymphotoxin B receptor|lymphotoxin beta receptor|tumor necrosis factor C receptor|tumor necrosis factor receptor superfamily, member 3
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Interactome
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Pathway
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Disease
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