PTPRF monoclonal antibody, clone 6D7C7
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: PTPRF-hIgGFc transfected HEK293 cell lysates with PTPRF monoclonal antibody, clone 6D7C7 (Cat # MAB21381).
Enzyme-linked Immunoabsorbent Assay
ELISA analysis with PTPRF monoclonal antibody, clone 6D7C7 (Cat # MAB21381).
Flow Cytometry
Flow cytometric analysis of HL-60 cells with PTPRF monoclonal antibody, clone 6D7C7 (Cat # MAB21381) (Green). Red: Negative Control.
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human PTPRF.
Immunogen
Recombinant protein corresponding to amino acids 1104-1163 of human PTPRF.
Host
Mouse
Theoretical MW (kDa)
213
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Flow Cytometry (1:200-1:400)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: PTPRF-hIgGFc transfected HEK293 cell lysates with PTPRF monoclonal antibody, clone 6D7C7 (Cat # MAB21381).Enzyme-linked Immunoabsorbent Assay
ELISA analysis with PTPRF monoclonal antibody, clone 6D7C7 (Cat # MAB21381).Flow Cytometry
Flow cytometric analysis of HL-60 cells with PTPRF monoclonal antibody, clone 6D7C7 (Cat # MAB21381) (Green). Red: Negative Control. -
Gene Info — PTPRF
Entrez GeneID
5792Protein Accession#
P10586Gene Name
PTPRF
Gene Alias
FLJ43335, FLJ45062, FLJ45567, LAR
Gene Description
protein tyrosine phosphatase, receptor type, F
Omim ID
179590Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains three Ig-like domains, and nine non-Ig like domains similar to that of neural-cell adhesion molecule. This PTP was shown to function in the regulation of epithelial cell-cell contacts at adherents junctions, as well as in the control of beta-catenin signaling. An increased expression level of this protein was found in the insulin-responsive tissue of obese, insulin-resistant individuals, and may contribute to the pathogenesis of insulin resistance. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. [provided by RefSeq
Other Designations
LCA-homolog|OTTHUMP00000008684|leukocyte antigen-related (LAR) PTP receptor|leukocyte antigen-related tyrosine phosphatase|protein tyrosine phosphatase, receptor type, F polypeptide|receptor-linked protein-tyrosine phosphatase LAR
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Interactome
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Disease
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