JAG1 monoclonal antibody, clone 7C7E1
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human JAG1.
Immunogen
Recombinant protein corresponding to amino acids 47-212 of human JAG1.
Host
Mouse
Theoretical MW (kDa)
133.8
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Flow Cytometry (1:200-1:400)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Enzyme-linked Immunoabsorbent Assay
ELISA analysis with JAG1 monoclonal antibody, clone 7C7E1 (Cat # MAB21374).Flow Cytometry
Flow cytometric analysis of HL-60 cells with JAG1 monoclonal antibody, clone 7C7E1 (Cat # MAB21374) (Green). Red: Negative Control. -
Gene Info — JAG1
Entrez GeneID
182Protein Accession#
P78504Gene Name
JAG1
Gene Alias
AGS, AHD, AWS, CD339, HJ1, JAGL1, MGC104644
Gene Description
jagged 1 (Alagille syndrome)
Gene Ontology
HyperlinkGene Summary
The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis. [provided by RefSeq
Other Designations
OTTHUMP00000030278|jagged 1
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Interactome
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