LILRB5 monoclonal antibody, clone 6D3C8
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human LILRB5.
Immunogen
Recombinant protein corresponding to amino acids 24-164 of human LILRB5.
Host
Mouse
Theoretical MW (kDa)
64.1
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Flow Cytometry (1:200-1:400)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: LILRB5-hIgGFc transfected HEK293 cell lysates with LILRB5 monoclonal antibody, clone 6D3C8 (Cat # MAB21372).Enzyme-linked Immunoabsorbent Assay
ELISA analysis with LILRB5 monoclonal antibody, clone 6D3C8 (Cat # MAB21372).Flow Cytometry
Flow cytometric analysis of HL-60 cells with LILRB5 monoclonal antibody, clone 6D3C8 (Cat # MAB21372) (Green). Red: Negative Control. -
Gene Info — LILRB5
Entrez GeneID
10990Protein Accession#
O75023Gene Name
LILRB5
Gene Alias
CD85C, LIR-8, LIR8
Gene Description
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5
Omim ID
604814Gene Ontology
HyperlinkGene Summary
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). Several other LIR subfamily B receptors are expressed on immune cells where they bind to MHC class I molecules on antigen-presenting cells and inhibit stimulation of an immune response. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
leukocyte immunoglobulin-like receptor 8|leukocyte immunoglobulin-like receptor, subfamily B, member 5
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