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Last updated: 2021/6/20

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PTPRJ monoclonal antibody, clone 1D2C11 

  • Catalog # : MAB21367
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant human PTPRJ.
  • Immunogen:
  • Recombinant protein corresponding to amino acids 36-210 of human PTPRJ.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 146
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Isotype:
  • IgG2b
  • Recommend Usage:
  • ELISA (1:10000)
    Flow Cytometry (1:200-1:400)
    Western Blot (1:500-1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.05% sodium azide).
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western Blot analysis of Lane 1: HEK293 and Lane 2: PTPRJ-hIgGFc transfected HEK293 cell lysates with PTPRJ monoclonal antibody, clone 1D2C11 (Cat # MAB21367).
  • Enzyme-linked Immunoabsorbent Assay
  • Enzyme-linked Immunoabsorbent Assay
  • ELISA analysis with PTPRJ monoclonal antibody, clone 1D2C11 (Cat # MAB21367).
  • Flow Cytometry
  • Flow Cytometry
  • Flow cytometric analysis of HL-60 cells with PTPRJ monoclonal antibody, clone 1D2C11 (Cat # MAB21367) (Green). Red: Negative Control.
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Enzyme-linked Immunoabsorbent Assay
  • Enzyme-linked Immunoabsorbent Assay
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 5795
  • Gene Name:
  • PTPRJ
  • Gene Alias:
  • CD148,DEP1,HPTPeta,R-PTP-ETA,SCC1
  • Gene Description:
  • protein tyrosine phosphatase, receptor type, J
  • Gene Summary:
  • The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This protein is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells. This protein can also dephosphorylate the PDGF beta receptor, and may be involved in UV-induced signal transduction. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • CD148 antigen,human density enhanced phosphatase-1,protein tyrosine phosphatase, receptor type, J polypeptide,receptor-type tyrosine-protein phosphatase eta,susceptibility to colon cancer 1, mouse, homolog of
  • Gene Pathway
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