TREM1 monoclonal antibody, clone 6B12D1
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: TREM1-hIgGFc transfected HEK293 cell lysates with TREM1 monoclonal antibody, clone 6B12D1 (Cat # MAB21361).
Enzyme-linked Immunoabsorbent Assay
ELISA analysis with TREM1 monoclonal antibody, clone 6B12D1 (Cat # MAB21361).
Flow Cytometry
Flow cytometric analysis of HL-60 cells with TREM1 monoclonal antibody, clone 6B12D1 (Cat # MAB21361) (Green). Red: Negative Control.
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human TREM1.
Immunogen
Recombinant protein corresponding to amino acids 21-205 of human TREM1.
Host
Mouse
Theoretical MW (kDa)
26.4
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Flow Cytometry (1:200-1:400)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: TREM1-hIgGFc transfected HEK293 cell lysates with TREM1 monoclonal antibody, clone 6B12D1 (Cat # MAB21361).Enzyme-linked Immunoabsorbent Assay
ELISA analysis with TREM1 monoclonal antibody, clone 6B12D1 (Cat # MAB21361).Flow Cytometry
Flow cytometric analysis of HL-60 cells with TREM1 monoclonal antibody, clone 6B12D1 (Cat # MAB21361) (Green). Red: Negative Control. -
Gene Info — TREM1
Entrez GeneID
54210Protein Accession#
Q9NP99Gene Name
TREM1
Gene Alias
TREM-1
Gene Description
triggering receptor expressed on myeloid cells 1
Omim ID
605085Gene Ontology
HyperlinkGene Summary
Monocyte/macrophage- and neutrophil-mediated inflammatory responses can be stimulated through a variety of receptors, including G protein-linked 7-transmembrane receptors (e.g., FPR1; MIM 136537), Fc receptors (see MIM 146790), CD14 (MIM 158120) and Toll-like receptors (e.g., TLR4; MIM 603030), and cytokine receptors (e.g., IFNGR1; MIM 107470). Engagement of these receptors can also prime myeloid cells to respond to other stimuli. Myeloid cells express receptors belonging to the Ig superfamily, such as TREM1, or to the C-type lectin superfamily. Depending on their transmembrane and cytoplasmic sequence structure, these receptors have either activating (e.g., KIR2DS1; MIM 604952) or inhibitory functions (e.g., KIR2DL1; MIM 604936).[supplied by OMIM
Other Designations
OTTHUMP00000016370|triggering-receptor TREM1
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Interactome
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Disease
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