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Last updated: 2021/6/20

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TEK monoclonal antibody, clone 3F5B9 

  • Catalog # : MAB21352
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant human TEK.
  • Immunogen:
  • Recombinant protein corresponding to amino acids 571-748 of human TEK.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 125.8
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Isotype:
  • IgG2b
  • Recommend Usage:
  • ELISA (1:10000)
    Flow Cytometry (1:200-1:400)
    Western Blot (1:500-1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.05% sodium azide).
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western Blot analysis of Lane 1: HEK293 and Lane 2: TEK-hIgGFc transfected HEK293 cell lysates with TEK monoclonal antibody, clone 3F5B9 (Cat # MAB21352).
  • Enzyme-linked Immunoabsorbent Assay
  • Enzyme-linked Immunoabsorbent Assay
  • ELISA analysis with TEK monoclonal antibody, clone 3F5B9 (Cat # MAB21352).
  • Flow Cytometry
  • Flow Cytometry
  • Flow cytometric analysis of K562 cells with TEK monoclonal antibody, clone 3F5B9 (Cat # MAB21352) (Green). Red: Negative Control.
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Enzyme-linked Immunoabsorbent Assay
  • Enzyme-linked Immunoabsorbent Assay
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 7010
  • Gene Name:
  • TEK
  • Gene Alias:
  • CD202B,TIE-2,TIE2,VMCM,VMCM1
  • Gene Description:
  • TEK tyrosine kinase, endothelial
  • Gene Summary:
  • The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations; the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis. TEK is closely related to the TIE receptor tyrosine kinase. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000021167,soluble TIE2 variant 1,soluble TIE2 variant 2
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