TNFRSF18 monoclonal antibody, clone 6H8B9
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: TNFRSF18-hIgGFc transfected HEK293 cell lysates with TNFRSF18 monoclonal antibody, clone 6H8B9 (Cat # MAB21346).
Enzyme-linked Immunoabsorbent Assay
ELISA analysis with TNFRSF18 monoclonal antibody, clone 6H8B9 (Cat # MAB21346).
Flow Cytometry
Flow cytometric analysis of HL-60 cells with TNFRSF18 monoclonal antibody, clone 6H8B9 (Cat # MAB21346) (Green). Red: Negative Control.
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human TNFRSF18.
Immunogen
Recombinant protein corresponding to amino acids 184-241 of human TNFRSF18.
Host
Mouse
Theoretical MW (kDa)
26
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Flow Cytometry (1:200-1:400)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: TNFRSF18-hIgGFc transfected HEK293 cell lysates with TNFRSF18 monoclonal antibody, clone 6H8B9 (Cat # MAB21346).Enzyme-linked Immunoabsorbent Assay
ELISA analysis with TNFRSF18 monoclonal antibody, clone 6H8B9 (Cat # MAB21346).Flow Cytometry
Flow cytometric analysis of HL-60 cells with TNFRSF18 monoclonal antibody, clone 6H8B9 (Cat # MAB21346) (Green). Red: Negative Control. -
Gene Info — TNFRSF18
Entrez GeneID
8784Protein Accession#
Q9Y5U5Gene Name
TNFRSF18
Gene Alias
AITR, GITR, GITR-D
Gene Description
tumor necrosis factor receptor superfamily, member 18
Omim ID
603905Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq
Other Designations
OTTHUMP00000001519|OTTHUMP00000001520|OTTHUMP00000001521|TNF receptor superfamily activation-inducible protein|activation-inducible TNFR family receptor|glucocorticoid-induced TNFR-related protein
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Interactome
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Pathway
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Disease
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