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Last updated: 2021/6/13

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IL21R monoclonal antibody, clone 8H10G4D12 

  • Catalog # : MAB21341
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant human IL21R.
  • Immunogen:
  • Recombinant protein corresponding to amino acids 20-232 of human IL21R.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 59.1
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Recommend Usage:
  • ELISA (1:10000)
    Flow Cytometry (1:200-1:400)
    Western Blot (1:500-1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.05% sodium azide).
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western Blot analysis of Lane 1: HEK293 and Lane 2: IL21R-hIgGFc transfected HEK293 cell lysates with IL21R monoclonal antibody, clone 8H10G4D12 (Cat # MAB21341).
  • Enzyme-linked Immunoabsorbent Assay
  • Enzyme-linked Immunoabsorbent Assay
  • ELISA analysis with IL21R monoclonal antibody, clone 8H10G4D12 (Cat # MAB21341).
  • Flow Cytometry
  • Flow Cytometry
  • Flow cytometric analysis of K562 cells with IL21R monoclonal antibody, clone 8H10G4D12 (Cat # MAB21341) (Green). Red: Negative Control.
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Enzyme-linked Immunoabsorbent Assay
  • Enzyme-linked Immunoabsorbent Assay
  • enlarge
  • Gene Information
  • Gene Name:
  • IL21R
  • Gene Alias:
  • MGC10967,NILR
  • Gene Description:
  • interleukin 21 receptor
  • Gene Summary:
  • The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq
  • Other Designations:
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