IL21R monoclonal antibody, clone 8H10G4D12
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: IL21R-hIgGFc transfected HEK293 cell lysates with IL21R monoclonal antibody, clone 8H10G4D12 (Cat # MAB21341).
Enzyme-linked Immunoabsorbent Assay
ELISA analysis with IL21R monoclonal antibody, clone 8H10G4D12 (Cat # MAB21341).
Flow Cytometry
Flow cytometric analysis of K562 cells with IL21R monoclonal antibody, clone 8H10G4D12 (Cat # MAB21341) (Green). Red: Negative Control.
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human IL21R.
Immunogen
Recombinant protein corresponding to amino acids 20-232 of human IL21R.
Host
Mouse
Theoretical MW (kDa)
59.1
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Flow Cytometry (1:200-1:400)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: IL21R-hIgGFc transfected HEK293 cell lysates with IL21R monoclonal antibody, clone 8H10G4D12 (Cat # MAB21341).Enzyme-linked Immunoabsorbent Assay
ELISA analysis with IL21R monoclonal antibody, clone 8H10G4D12 (Cat # MAB21341).Flow Cytometry
Flow cytometric analysis of K562 cells with IL21R monoclonal antibody, clone 8H10G4D12 (Cat # MAB21341) (Green). Red: Negative Control. -
Gene Info — IL21R
Entrez GeneID
50615Protein Accession#
Q9HBE5Gene Name
IL21R
Gene Alias
MGC10967, NILR
Gene Description
interleukin 21 receptor
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq
Other Designations
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Interactome
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