TLR2 monoclonal antibody, clone 7C1H9
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human TLR2.
Immunogen
Recombinant protein corresponding to amino acids 21-197 of human TLR2.
Host
Mouse
Theoretical MW (kDa)
89.8
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: TLR2-hIgGFc transfected HEK293 cell lysates with TLR2 monoclonal antibody, clone 7C1H9 (Cat # MAB21340).Enzyme-linked Immunoabsorbent Assay
ELISA analysis with TLR2 monoclonal antibody, clone 7C1H9 (Cat # MAB21340). -
Gene Info — TLR2
Entrez GeneID
7097Protein Accession#
O60603Gene Name
TLR2
Gene Alias
CD282, TIL4
Gene Description
toll-like receptor 2
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB. [provided by RefSeq
Other Designations
toll/interleukin 1 receptor-like 4
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