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Last updated: 2021/6/20

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TIGIT monoclonal antibody, clone 4C5B9 

  • Catalog # : MAB21338
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant human TIGIT.
  • Immunogen:
  • Recombinant protein corresponding to amino acids 22-141 of human TIGIT.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 26.3
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Recommend Usage:
  • ELISA (1:10000)
    Flow Cytometry (1:200-1:400)
    Western Blot (1:500-1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.05% sodium azide).
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western Blot analysis of Lane 1: HEK293 and Lane 2: TIGIT-hIgGFc transfected HEK293 cell lysates with TIGIT monoclonal antibody, clone 4C5B9 (Cat # MAB21338).
  • Enzyme-linked Immunoabsorbent Assay
  • Enzyme-linked Immunoabsorbent Assay
  • ELISA analysis with TIGIT monoclonal antibody, clone 4C5B9 (Cat # MAB21338).
  • Flow Cytometry
  • Flow Cytometry
  • Flow cytometric analysis of K562 cells with TIGIT monoclonal antibody, clone 4C5B9 (Cat # MAB21338) (Green). Red: Negative Control.
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Enzyme-linked Immunoabsorbent Assay
  • Enzyme-linked Immunoabsorbent Assay
  • enlarge
  • Gene Information
  • Gene Name:
  • TIGIT
  • Gene Alias:
  • DKFZp667A205,FLJ39873,VSIG9,VSTM3
  • Gene Description:
  • T cell immunoreceptor with Ig and ITIM domains
  • Gene Summary:
  • This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses
  • Other Designations:
  • V-set and immunoglobulin domain containing 9,V-set and transmembrane domain containing 3
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