CHRM3 monoclonal antibody, clone 4A6B7
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human CHRM3.
Immunogen
Recombinant protein corresponding to human CHRM3.
Host
Mouse
Theoretical MW (kDa)
66
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Flow Cytometry (1:200-1:400)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: CHRM3-hIgGFc transfected HEK293 cell lysates with CHRM3 monoclonal antibody, clone 4A6B7 (Cat # MAB21328).Enzyme-linked Immunoabsorbent Assay
ELISA analysis with CHRM3 monoclonal antibody, clone 4A6B7 (Cat # MAB21328).Flow Cytometry
Flow cytometric analysis of Jurkat cells with CHRM3 monoclonal antibody, clone 4A6B7 (Cat # MAB21328) (Green). Red: Negative Control. -
Gene Info — CHRM3
Entrez GeneID
1131Protein Accession#
P20309Gene Name
CHRM3
Gene Alias
HM3
Gene Description
cholinergic receptor, muscarinic 3
Omim ID
118494Gene Ontology
HyperlinkGene Summary
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 3 controls smooth muscle contraction and its stimulation causes secretion of glandular tissue. [provided by RefSeq
Other Designations
m3 muscarinic receptor|muscarinic acetylcholine receptor M3
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