PLAUR monoclonal antibody, clone 1D1B11
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
-
Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human PLAUR.
Immunogen
Recombinant protein corresponding to amino acids 23-305 of human PLAUR.
Host
Mouse
Theoretical MW (kDa)
37
Reactivity
Human
Form
Liquid
Isotype
IgG2b
Recommend Usage
ELISA (1:10000)
Flow Cytometry (1:200-1:400)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: PLAUR-hIgGFc transfected HEK293 cell lysates with PLAUR monoclonal antibody, clone 1D1B11 (Cat # MAB21326).Enzyme-linked Immunoabsorbent Assay
ELISA analysis with PLAUR monoclonal antibody, clone 1D1B11 (Cat # MAB21326).Flow Cytometry
Flow cytometric analysis of K562 cells with PLAUR monoclonal antibody, clone 1D1B11 (Cat # MAB21326) (Green). Red: Negative Control. -
Gene Info — PLAUR
Entrez GeneID
5329Protein Accession#
Q03405Gene Name
PLAUR
Gene Alias
CD87, UPAR, URKR
Gene Description
plasminogen activator, urokinase receptor
Omim ID
173391Gene Ontology
HyperlinkGene Summary
This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined. [provided by RefSeq
Other Designations
monocyte activation antigen Mo3|u-plasminogen activator receptor form 2
-
Interactome
-
Pathway
-
Disease
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com