KRT6A monoclonal antibody, clone KRT6A/2368
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human basal cell carcinoma with KRT6A monoclonal antibody, clone KRT6A/2368 (Cat # MAB21274).
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Specification
Product Description
Mouse monoclonal antibody raised against full length recombinant human KRT6A.
Immunogen
Recombinant protein corresponding to full length human KRT6A.
Host
Mouse
Theoretical MW (kDa)
56
Reactivity
Human
Form
Liquid
Purification
Protein A/G purification
Isotype
IgG2a, kappa
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 10 mM PBS.
Storage Instruction
Store at -20 to -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human basal cell carcinoma with KRT6A monoclonal antibody, clone KRT6A/2368 (Cat # MAB21274). -
Gene Info — KRT6A
Entrez GeneID
3853Protein Accession#
P02538Gene Name
KRT6A
Gene Alias
CK6A, CK6C, CK6D, K6A, K6C, K6D, KRT6C, KRT6D
Gene Description
keratin 6A
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified; the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. This KRT6 gene in particular encodes the most abundant isoform. Mutations in these genes have been associated with pachyonychia congenita. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq
Other Designations
56 cytoskeletal type II keratin|K6D keratin|cytokeratin 6A|cytokeratin 6C|cytokeratin 6D|keratin 6C|keratin, epidermal type II, K6A|keratin, epidermal type II, K6C|keratin, type II cytoskeletal 6D|type II keratin isoform K6c
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