ICAM3 monoclonal antibody, clone 186-2G9
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Specification
Product Description
Mouse monoclonal antibody raised against human ICAM3.
Immunogen
Stimulated human leukocytes.
Host
Mouse
Theoretical MW (kDa)
110-160
Reactivity
Human
Form
Liquid
Purification
Protein A/G purification
Isotype
IgG2b, kappa
Recommend Usage
Blocking
Flow Cytometry (0.5-1 ug/106 cells in 0.1 mL)
Immunofluorescence (0.5-1 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 10 mM PBS.
Storage Instruction
Store at -20 to -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human tonsil with ICAM3 monoclonal antibody, clone 186-2G9 (Cat # MAB21240).Immunofluorescence
Blocking
Flow Cytometry
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Gene Info — ICAM3
Entrez GeneID
3385Protein Accession#
P32942Gene Name
ICAM3
Gene Alias
CD50, CDW50, ICAM-R
Gene Description
intercellular adhesion molecule 3
Omim ID
146631Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. [provided by RefSeq
Other Designations
intercellular adhesion molecule-3
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Interactome
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Pathway
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Disease
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