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Last updated: 2021/6/13

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GZMB monoclonal antibody, clone GZMB/2403 

  • Catalog # : MAB21215
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant human GZMB.
  • Immunogen:
  • Recombinant protein corresponding to amino acids 73-187 of human GZMB.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 29-32
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein G purification
  • Isotype:
  • IgG2b, kappa
  • Recommend Usage:
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1-2 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 10 mM PBS (0.05% BSA, 0.05% sodium azide).
  • Storage Instruction:
  • Store at 4°C.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human tonsil with GZMB monoclonal antibody, clone GZMB/2403 (Cat # MAB21215).
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
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  • Gene Information
  • Entrez GeneID:
  • 3002
  • Gene Name:
  • GZMB
  • Gene Alias:
  • CCPI,CGL-1,CGL1,CSP-B,CSPB,CTLA1,CTSGL1,HLP,SECT
  • Gene Description:
  • granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
  • Gene Summary:
  • Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein encoded by this gene is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response. [provided by RefSeq
  • Other Designations:
  • T-cell serine protease 1-3E,cathepsin G-like 1,cytotoxic serine protease B,fragmentin 2,granzyme B
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