ABO monoclonal antibody, clone HEB-29
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Specification
Product Description
Mouse monoclonal antibody raised against human ABO.
Immunogen
Mixture of erythrocytes of group B and glycoprotein fraction isolated from saliva of secretors with blood group B.
Host
Mouse
Reactivity
Human
Specificity
The antibody HEB-29 reacts with human blood group B. The specificity of the antibody HEB-29 was confirmed by comparison of specificity and reactivity to standard reagent using 5.000 samples of blood. MAb HEB-29 shows specific staining of erythrocytes and vascular epithelium of blood group B controls and no staining in group A controls.
Form
Liquid
Purification
Protein A/G purification
Isotype
IgM, kappa
Recommend Usage
Agglutination
ELISA (For coating)
Immunofluorescence (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 10 mM PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunofluorescence
Enzyme-linked Immunoabsorbent Assay
Agglutination
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Gene Info — ABO
Entrez GeneID
28Protein Accession#
P16442Gene Name
ABO
Gene Alias
A3GALNT, A3GALT1, GTB, NAGAT
Gene Description
ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
Omim ID
110300Gene Ontology
HyperlinkGene Summary
This gene encodes proteins related to the first discovered blood group system, ABO. Which allele is present in an individual determines the blood group. The 'O' blood group is caused by a deletion of guanine-258 near the N-terminus of the protein which results in a frameshift and translation of an almost entirely different protein. Individuals with the A, B, and AB alleles express glycosyltransferase activities that convert the H antigen into the A or B antigen. Other minor alleles have been found for this gene. [provided by RefSeq
Other Designations
ABO glycocyltransferase|ABO glycosyltransferase|B(A) alpha-1,3-galactosyltransferase|alpha 1-3-N-acetylgalactosaminyltransferase|histo-blood group A2 transferase|histo-blood group ABO protein
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Interactome
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Disease
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