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Last updated: 2021/6/20

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FUT3 monoclonal antibody, clone 2-25LE 

  • Catalog # : MAB21198
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against human FUT3.
  • Immunogen:
  • Mucin isolated from a human ovarian cyst fluid.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 45
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein A/G purification
  • Isotype:
  • IgG1, kappa
  • Recommend Usage:
  • Immunofluorescence (0.5-1 ug/mL)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 10 mM PBS.
  • Storage Instruction:
  • Store at -20 to -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunofluorescence
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunofluorescence
  • Gene Information
  • Entrez GeneID:
  • 2525
  • Gene Name:
  • FUT3
  • Gene Alias:
  • CD174,FT3B,FucT-III,LE,Les,MGC131739
  • Gene Description:
  • fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)
  • Gene Summary:
  • The Lewis histo-blood group system comprises a set of fucosylated glycosphingolipids that are synthesized by exocrine epithelial cells and circulate in body fluids. The glycosphingolipids function in embryogenesis, tissue differentiation, tumor metastasis, inflammation, and bacterial adhesion. They are secondarily absorbed to red blood cells giving rise to their Lewis phenotype. This gene is a member of the fucosyltransferase family, which catalyzes the addition of fucose to precursor polysaccharides in the last step of Lewis antigen biosynthesis. It encodes an enzyme with alpha(1,3)-fucosyltransferase and alpha(1,4)-fucosyltransferase activities. Mutations in this gene are responsible for the majority of Lewis antigen-negative phenotypes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene. [provided by RefSeq
  • Other Designations:
  • Lewis FT,alpha-(1,3/1,4)-fucosyltransferase,blood group Lewis alpha-4-fucosyltransferase,fucosyltransferase 3,galactoside 3(4)-L-fucosyltransferase
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