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CTSK monoclonal antibody, clone CTSK/2791 

  • Catalog # : MAB21165
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant human CTSK.
  • Immunogen:
  • Recombinant protein corresponding to amino acids 163-274 of human CTSK.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 39
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein A/G purification
  • Isotype:
  • IgG, kappa
  • Recommend Usage:
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1-2 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 10 mM PBS (0.05% BSA, 0.05% sodium azide).
  • Storage Instruction:
  • Store at 4°C.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human liver with CTSK monoclonal antibody, clone CTSK/2791 (Cat # MAB21165).
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 1513
  • Gene Name:
  • CTSK
  • Gene Alias:
  • CTS02,CTSO,CTSO1,CTSO2,MGC23107,PKND,PYCD
  • Gene Description:
  • cathepsin K
  • Gene Summary:
  • The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000032938,cathepsin O1,cathepsin O2,cathepsin X
  • Gene Pathway
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