CHGA monoclonal antibody, clone LK2H10 + PHE5 + CGA/414
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Specifications
Product Description
Mouse monoclonal antibody raised against human CHGA.
Immunogen
Human pheochromocytoma (LK2H10 & PHE5); Recombinant protein corresponding to full length human CHGA (CGA414).
Host
Mouse
Theoretical MW (kDa)
68-75
Reactivity
Human
Form
Liquid
Purification
Protein A/G purification
Isotype
IgG1, kappa
Recommend Usage
Flow Cytometry (0.5-1 ug/106 cells in 0.1 mL)
Immunofluorescence (0.5-1 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.25-0.5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 10 mM PBS.
Storage Instruction
Store at -20 to -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human small cell lung carcinoma with CHGA monoclonal antibody, clone LK2H10 + PHE5 + CGA/414 (Cat # MAB21152).Immunofluorescence
Flow Cytometry
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Gene Info — CHGA
Entrez GeneID
1113Protein Accession#
P10645Gene Name
CHGA
Gene Alias
CGA
Gene Description
chromogranin A (parathyroid secretory protein 1)
Omim ID
118910Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides; vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Other peptides, including chromostatin, beta-granin, WE-14 and GE-25, are also derived from the full-length protein. However, biological activities for these molecules have not been shown. [provided by RefSeq
Other Designations
betagranin (N-terminal fragment of chromogranin A)|chromogranin A|parathyroid secretory protein 1
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