OLIG2 monoclonal antibody, clone OLIG2/2400
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human OLIG2.
Immunogen
Recombinant protein corresponding to amino acids 1-141 of human OLIG2.
Host
Mouse
Theoretical MW (kDa)
30-40
Reactivity
Human
Form
Liquid
Purification
Protein A/G purification
Isotype
IgG1, kappa
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 10 mM PBS (0.05% BSA, 0.05% sodium azide).
Storage Instruction
Store at 4°C.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human cerebellum with OLIG2 monoclonal antibody, clone OLIG2/2400 (Cat # MAB21133). -
Gene Info — OLIG2
Entrez GeneID
10215Protein Accession#
Q13516Gene Name
OLIG2
Gene Alias
BHLHB1, OLIGO2, PRKCBP2, RACK17, bHLHe19
Gene Description
oligodendrocyte lineage transcription factor 2
Omim ID
606386Gene Ontology
HyperlinkGene Summary
This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14;21)(q11.2;q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome. [provided by RefSeq
Other Designations
OTTHUMP00000067569|OTTHUMP00000067570|basic domain, helix-loop-helix protein, class B, 1|human protein kinase C-binding protein RACK17|oligodendrocyte-specific bHLH transcription factor 2|protein kinase C binding protein 2
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