GSTM2 monoclonal antibody, clone CPTC-GSTMu2-2
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Specification
Product Description
Mouse monoclonal antibody raised against full length recombinant human GSTM2.
Immunogen
Recombinant protein corresponding to full length human GSTM2.
Host
Mouse
Reactivity
Human
Form
Liquid
Purification
Protein A/G purification
Isotype
IgG1
Recommend Usage
Immunofluorescence (0.5-1ug/mL)
Immunohistochemistry (Formalin-fixed) (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 10 mM PBS (0.05% BSA, 0.05% sodium azide)
Storage Instruction
Store at 2 to 8°C.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human Breast Carcinoma using GSTM2 monoclonal antibody, clone CPTC-GSTMu2-2.Immunofluorescence
Immunofluorescent staining of human HeLa cells labeling GSTM2 with GSTM2 monoclonal antibody, clone CPTC-GSTMu2-2. -
Gene Info — GSTM2
Entrez GeneID
2946Protein Accession#
P28161Gene Name
GSTM2
Gene Alias
GST4, GSTM, GSTM2-2, GTHMUS, MGC117303
Gene Description
glutathione S-transferase mu 2 (muscle)
Omim ID
138380Gene Ontology
HyperlinkGene Summary
Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. [provided by RefSeq
Other Designations
GST class-mu 2|GST, muscle|OTTHUMP00000013351|S-(hydroxyalkyl)glutathione lyase M2|glutathione S-alkyltransferase M2|glutathione S-aralkyltransferase M2|glutathione S-aryltransferase M2|glutathione S-transferase 4|glutathione S-transferase M1|glutathione
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