AKR1B1 monoclonal antibody, clone CPTC-AKR1B1-3
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Specification
Product Description
Mouse monoclonal antibody raised against full length recombinant human AKR1B1.
Immunogen
Recombinant protein corresponding to full length human AKR1B1.
Host
Mouse
Theoretical MW (kDa)
37
Reactivity
Human
Form
Liquid
Purification
Protein A/G purification
Isotype
IgG1, kappa
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL)
Western Blot (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 10 mM PBS (0.05% BSA, 0.05% sodium azide).
Storage Instruction
Store at 2 to 8°C.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human prostate cancer with AKR1B1 monoclonal antibody, clone CPTC-AKR1B1-3 (Cat # MAB20973). -
Gene Info — AKR1B1
Entrez GeneID
231Protein Accession#
P15121Gene Name
AKR1B1
Gene Alias
ADR, ALDR1, ALR2, AR, MGC1804
Gene Description
aldo-keto reductase family 1, member B1 (aldose reductase)
Omim ID
103880Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for this gene. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database. [provided by RefSeq
Other Designations
Lii5-2 CTCL tumor antigen|aldehyde reductase 1|aldo-keto reductase family 1, member B1|aldose reductase|low Km aldose reductase
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Interactome
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Disease
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