FLG monoclonal antibody, clone FLG/1945
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human skin with FLG monoclonal antibody, clone FLG/1945 (Cat # MAB20967).
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human FLG.
Immunogen
Recombinant protein corresponding to amino acids 998-1104 of human FLG.
Host
Mouse
Reactivity
Human
Form
Liquid
Purification
Protein A/G purification
Isotype
IgG2b, kappa
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 10 mM PBS (0.05% BSA, 0.05% sodium azide).
Storage Instruction
Store at 2 to 8°C.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human skin with FLG monoclonal antibody, clone FLG/1945 (Cat # MAB20967). -
Gene Info — FLG
Entrez GeneID
2312Protein Accession#
P20930Gene Name
FLG
Gene Alias
ATOD2
Gene Description
filaggrin
Gene Ontology
HyperlinkGene Summary
Profilaggrin is a major protein component of the keratohyalin granules of mammalian epidermis. It is initially expressed as a large polyprotein precursor which is subsequently proteolytically processed into individual functional filaggrin molecules. The filaggrins show wide species variations and their aberrant expression has been implicated in a number of keratinizing disorders (Baden et al., 1974 [PubMed 4132224]; Holbrook et al., 1982 [PubMed 6174530]; Sybert et al., 1985 [PubMed 2579164]).[supplied by OMIM
Other Designations
OTTHUMP00000014057|epidermal filaggrin
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Interactome
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Disease
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