TYR monoclonal antibody, clone AAHE-20
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic peptide of human TYR.
Immunogen
A synthetic peptide corresponding to human TYR.
Host
Rabbit
Theoretical MW (kDa)
60.393
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunocytochemistry (1:50-1:200)
Immunofluorescence (1:50-1:200)
Immunohistochemistry (1:50-1:200)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western Blot analysis of human melanoma lysate with TYR monoclonal antibody, clone AAHE-20 (Cat # MAB20823).Immunohistochemistry
Immunocytochemistry
Immunofluorescence
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Gene Info — TYR
Entrez GeneID
7299Protein Accession#
P14679Gene Name
TYR
Gene Alias
OCA1A, OCAIA, SHEP3
Gene Description
tyrosinase (oculocutaneous albinism IA)
Gene Ontology
HyperlinkGene Summary
The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene. [provided by RefSeq
Other Designations
tyrosinase
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Interactome
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Pathway
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Disease
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