TRAF4 monoclonal antibody, clone BGH-20
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More Files
- More Functions
Western Blot (Cell lysate)
Western Blot analysis of HeLa cell lysate with TRAF4 monoclonal antibody, clone BGH-20 (Cat # MAB20802).
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic peptide of human TRAF4.
Immunogen
A synthetic peptide corresponding to human TRAF4.
Host
Rabbit
Theoretical MW (kDa)
53.543
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Flow Cytometry (1:50)
Immunocytochemistry (1:50-1:200)
Immunofluorescence (1:50-1:200)
Western Blot (1:1000-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot analysis of HeLa cell lysate with TRAF4 monoclonal antibody, clone BGH-20 (Cat # MAB20802).Immunocytochemistry
Immunofluorescence
Flow Cytometry
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Gene Info — TRAF4
Entrez GeneID
9618Protein Accession#
Q9BUZ4Gene Name
TRAF4
Gene Alias
CART1, MLN62, RNF83
Gene Description
TNF receptor-associated factor 4
Omim ID
602464Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. The encoded protein has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK. Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined. [provided by RefSeq
Other Designations
cysteine-rich domain associated with ring and TRAF domain|malignant 62|tumor necrosis receptor-associated factor 4A
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Interactome
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Pathway
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Disease
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