TGFBR2 monoclonal antibody, clone ABFE-20
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
-
Specification
Product Description
Rabbit monoclonal antibody raised against synthetic peptide of human TGFBR2.
Immunogen
A synthetic peptide corresponding to human TGFBR2.
Host
Rabbit
Theoretical MW (kDa)
64.568
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot (Cell lysate)
Western Blot analysis of A549 cell lysate with TGFBR2 monoclonal antibody, clone ABFE-20 (Cat # MAB20776). -
Gene Info — TGFBR2
Entrez GeneID
7048Protein Accession#
P37173Gene Name
TGFBR2
Gene Alias
AAT3, FAA3, LDS1B, LDS2B, MFS2, RIIC, TAAD2, TGFR-2, TGFbeta-RII
Gene Description
transforming growth factor, beta receptor II (70/80kDa)
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized. [provided by RefSeq
Other Designations
TGF-beta receptor type IIB|TGF-beta type II receptor|transforming growth factor beta receptor type IIC|transforming growth factor, beta receptor II|transforming growth factor, beta receptor II (70-80kD)
-
Interactome
-
Pathway
-
Disease
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com