SDC1 monoclonal antibody, clone AbS91
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic peptide of human SDC1.
Immunogen
A synthetic peptide corresponding to human SDC1.
Host
Rabbit
Theoretical MW (kDa)
32.462
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunocytochemistry (1:50-1:200)
Immunofluorescence (1:50-1:200)
Immunohistochemistry (1:100-1:500)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot analysis of Ramos cell lysate with SDC1 monoclonal antibody, clone AbS91 (Cat # MAB20765).Immunohistochemistry
Immunocytochemistry
Immunofluorescence
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Gene Info — SDC1
Entrez GeneID
6382Protein Accession#
P18827Gene Name
SDC1
Gene Alias
CD138, SDC, SYND1, syndecan
Gene Description
syndecan 1
Omim ID
186355Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein. [provided by RefSeq
Other Designations
CD138 antigen|OTTHUMP00000115942|heparan sulfate proteoglycan fibroblast growth factor receptor|syndecan proteoglycan 1
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Interactome
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Disease
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