STIM1 monoclonal antibody, clone HEC-19
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More Files
- More Functions
Western Blot (Cell lysate)
Western Blot analysis of HeLa cell lysate with STIM1 monoclonal antibody, clone HEC-19 (Cat # MAB20756).
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic peptide of human STIM1.
Immunogen
A synthetic peptide corresponding to human STIM1.
Host
Rabbit
Theoretical MW (kDa)
77.423
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
Immunoprecipitation (1:50)
Western Blot (1:1000-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot analysis of HeLa cell lysate with STIM1 monoclonal antibody, clone HEC-19 (Cat # MAB20756).Immunohistochemistry
Immunoprecipitation
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Gene Info — STIM1
Entrez GeneID
6786Protein Accession#
Q13586Gene Name
STIM1
Gene Alias
D11S4896E, GOK
Gene Description
stromal interaction molecule 1
Omim ID
605921Gene Ontology
HyperlinkGene Summary
This gene encodes a type 1 transmembrane protein that mediates Ca2+ influx after depletion of intracellular Ca2+ stores by gating of store-operated Ca2+ influx channels (SOCs). It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region, as well as early hematopoiesis, by mediating attachment to stromal cells. This gene is oriented in a head-to-tail configuration with the ribonucleotide reductase 1 gene (RRM1), with the 3' end of this gene situated 1.6 kb from the 5' end of the RRM1 gene
Other Designations
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