STAT6 monoclonal antibody, clone BOC-19
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic peptide of human STAT6.
Immunogen
A synthetic peptide corresponding to human STAT6.
Host
Rabbit
Theoretical MW (kDa)
94.135
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Flow Cytometry (1:50)
Immunocytochemistry (1:50-1:200)
Immunofluorescence (1:50-1:200)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot analysis of Lane 1: Daudi and Lane 2: HeLa cell lysates with STAT6 monoclonal antibody, clone BOC-19 (Cat # MAB20752).Immunocytochemistry
Immunofluorescence
Flow Cytometry
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Gene Info — STAT6
Entrez GeneID
6778Protein Accession#
P42226Gene Name
STAT6
Gene Alias
D12S1644, IL-4-STAT, STAT6B, STAT6C
Gene Description
signal transducer and activator of transcription 6, interleukin-4 induced
Omim ID
601512Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. [provided by RefSeq
Other Designations
STAT, interleukin4-induced|signal transducer and activator of transcription 6|transcription factor IL-4 STAT
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