SMC3 monoclonal antibody, clone AACO-19
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic peptide of human SMC3.
Immunogen
A synthetic peptide corresponding to human SMC3.
Host
Rabbit
Theoretical MW (kDa)
141.542
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Flow Cytometry (1:50)
Immunocytochemistry (1:50-1:200)
Immunofluorescence (1:50-1:200)
Immunohistochemistry (1:50-1:200)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot analysis of HeLa cell lysate with SMC3 monoclonal antibody, clone AACO-19 (Cat # MAB20723).Immunohistochemistry
Immunocytochemistry
Immunofluorescence
Flow Cytometry
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Gene Info — SMC3
Entrez GeneID
9126Protein Accession#
Q9UQE7Gene Name
SMC3
Gene Alias
BAM, BMH, CDLS3, CSPG6, HCAP, SMC3L1
Gene Description
structural maintenance of chromosomes 3
Gene Ontology
HyperlinkGene Summary
This gene belongs to the SMC3 subfamily of SMC proteins. The encoded protein occurs in certain cell types as either an intracellular, nuclear protein or a secreted protein. The nuclear form, known as structural maintenance of chromosomes 3, is a component of the multimeric cohesin complex that holds together sister chromatids during mitosis, enabling proper chromosome segregation. Post-translational modification of the encoded protein by the addition of chondroitin sulfate chains gives rise to the secreted proteoglycan bamacan, an abundant basement membrane protein. [provided by RefSeq
Other Designations
OTTHUMP00000020477|bamacan proteoglycan|basement membrane-associated chondroitin proteoglycan|chondroitin sulfate proteoglycan 6 (bamacan)|chromosome-associated polypeptide
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Interactome
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Pathway
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Disease
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