SIRT5 monoclonal antibody, clone HHE-19
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic peptide of human SIRT5.
Immunogen
A synthetic peptide corresponding to human SIRT5.
Host
Rabbit
Theoretical MW (kDa)
33.881
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Western Blot (1:1000-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot analysis of HeLa cell lysate with SIRT5 monoclonal antibody, clone HHE-19 (Cat # MAB20712). -
Gene Info — SIRT5
Entrez GeneID
23408Protein Accession#
Q9NXA8Gene Name
SIRT5
Gene Alias
FLJ36950, SIR2L5
Gene Description
sirtuin (silent mating type information regulation 2 homolog) 5 (S. cerevisiae)
Omim ID
604483Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class III of the sirtuin family. Alternative splicing of this gene results in two transcript variants. [provided by RefSeq
Other Designations
OTTHUMP00000016054|OTTHUMP00000016055|silent mating type information regulation 2, S.cerevisiae, homolog 5|sir2-like 5|sirtuin 5|sirtuin type 5
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Interactome
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Disease
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