SFRP1 monoclonal antibody, clone ABBA-19
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic peptide of human SFRP1.
Immunogen
A synthetic peptide corresponding to human SFRP1.
Host
Rabbit
Theoretical MW (kDa)
35.386
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunocytochemistry (1:50-1:200)
Immunofluorescence (1:50-1:200)
Immunohistochemistry (1:50-1:200)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot analysis of A375 cell lysate with SFRP1 monoclonal antibody, clone ABBA-19 (Cat # MAB20704).Immunohistochemistry
Immunocytochemistry
Immunofluorescence
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Gene Info — SFRP1
Entrez GeneID
6422Protein Accession#
Q8N474Gene Name
SFRP1
Gene Alias
FRP, FRP-1, FRP1, FrzA, SARP2
Gene Description
secreted frizzled-related protein 1
Omim ID
604156Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling; epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt-pathway which is associated with cancer. This gene may also be involved in determining the polarity of photoreceptor cells in the retina. [provided by RefSeq
Other Designations
secreted apoptosis-related protein 2
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Interactome
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Pathway
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Disease
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