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Last updated: 2022/5/22

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SDHB monoclonal antibody, clone ABDF-19 

  • Catalog # : MAB20699
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against synthetic peptide of human SDHB.
  • Immunogen:
  • A synthetic peptide corresponding to human SDHB.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 31.63
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Flow Cytometry (1:50)
    Immunohistochemistry (1:50-1:200)
    Immunoprecipitation (1:50)
    Western Blot (1:500-1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
  • Storage Instruction:
  • Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western Blot analysis of A431 cell lysate with SDHB monoclonal antibody, clone ABDF-19 (Cat # MAB20699).
  • Immunohistochemistry
  • Immunoprecipitation
  • Flow Cytometry
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry
  • Immunoprecipitation
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 6390
  • Gene Name:
  • SDHB
  • Gene Alias:
  • FLJ92337,IP,PGL4,SDH,SDH1,SDHIP
  • Gene Description:
  • succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
  • Gene Summary:
  • Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000002396,OTTHUMP00000044624,iron-sulfur subunit
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