RHOA/RHOB/RHOC monoclonal antibody, clone DGF-18
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More Files
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic peptide of human RHOA/RHOB/RHOC.
Immunogen
A synthetic peptide corresponding to human RHOA/RHOB/RHOC.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Flow Cytometry (1:200)
Immunocytochemistry (1:100-1:500)
Immunofluorescence (1:100-1:500)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:500-1:1000)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot analysis of Lane 1: Jurkat and Lane 2: NIH/3T3 cell lysates with RHOA/RHOB/RHOC monoclonal antibody, clone DGF-18 (Cat # MAB20672).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human lung carcinoma with RHOA/RHOB/RHOC monoclonal antibody, clone DGF-18 (Cat # MAB20672).Immunocytochemistry
Immunofluorescence
Flow Cytometry
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Gene Info — RHOA
Entrez GeneID
387Protein Accession#
P61586;P62745;P08134Gene Name
RHOA
Gene Alias
ARH12, ARHA, RHO12, RHOH12
Gene Description
ras homolog gene family, member A
Omim ID
165390Gene Ontology
HyperlinkGene Summary
O
Other Designations
Aplysia ras-related homolog 12|oncogene RHO H12|small GTP binding protein RhoA
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Gene Info — RHOB
Entrez GeneID
388Protein Accession#
P61586;P62745;P08134Gene Name
RHOB
Gene Alias
ARH6, ARHB, MST081, MSTP081, RHOH6
Gene Description
ras homolog gene family, member B
Omim ID
165370Gene Ontology
HyperlinkGene Summary
O
Other Designations
Aplysia RAS-related homolog 6|oncogene RHO H6
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Gene Info — RHOC
Entrez GeneID
389Protein Accession#
P61586;P62745;P08134Gene Name
RHOC
Gene Alias
ARH9, ARHC, H9, MGC1448, MGC61427, RHOH9
Gene Description
ras homolog gene family, member C
Omim ID
165380Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq
Other Designations
OTTHUMP00000013675|OTTHUMP00000013676|OTTHUMP00000013802|OTTHUMP00000013805|OTTHUMP00000013807|OTTHUMP00000013809|RAS-related homolog 9|Rho-related GTP-binding protein RhoC|oncogene RHO H9|rhoC GTPase|small GTP binding protein RhoC
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Interactome
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Pathway
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Disease
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