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Last updated: 2016/12/4
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TGFBI monoclonal antibody, clone k1H12

  • Catalog # : MAB2058
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant TGFBI.
  • Immunogen:
  • Recombinant protein corresponding to amino acids 502-636 of human TGFBI.
  • Host:
  • Mouse
  • Reactivity:
  • Human, Mouse
  • Form:
  • Liquid
  • Isotype:
  • IgG2a, kappa
  • Quality Control Testing:
  • Antibody Reactive Against Recombinant Protein.
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4 (0.09% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • 3.
  • BIGH3 mutation spectrum in corneal dystrophies.
    Munier FL, Frueh BE, Othenin-Girard P, Uffer S, Cousin P, Wang MX, Heon E, Black GC, Blasi MA, Balestrazzi E, Lorenz B, Escoto R, Barraquer R, Hoeltzenbein M, Gloor B, Fossarello M, Singh AD, Arsenijevic Y, Zografos L, Schorderet DF.Invest Ophthalmol Vis Sci. 2002 Apr;43(4):949-54.
  • Applications
  • Western Blot
  • Western Blot
  • Cell lysates of HeLa (lane 1), Jurkat (lane 2), 293T (lane 3) and the extracts of mouse liver tissue (lane 4) (20 ug) were resolved by SDS-PAGE and probed with TGFBI monoclonal antibody, clone k1H12 (Cat # MAB2058) (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.
  • ELISA
  • Application Image
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 7045
  • Gene Name:
  • TGFBI
  • Gene Alias:
  • BIGH3,CDB1,CDG2,CDGG1,CSD,CSD1,CSD2,CSD3,EBMD,LCD1
  • Gene Description:
  • transforming growth factor, beta-induced, 68kDa
  • Gene Summary:
  • This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy. [provided by RefSeq
  • Other Designations:
  • RGD-containing collagen-associated protein,kerato-epithelin
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