GRIA1 (phospho S845) monoclonal antibody, clone GFH-7

Product Description:
Rabbit monoclonal antibody raised against synthetic phosphopeptide of human GRIA1.

Immunogen:
A synthetic phosphopeptide corresponding to residues surrounding S845 of human GRIA1.

Recommend Usage:
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.

Storage Buffer:
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.4-0.5 mg/mL BSA, 0.02% sodium azide).

Storage Instruction:
Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

Note:
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Western Blot (Cell lysate)
Western Blot analysis of (1) Human brain lysate treated with Lambda phosphatase lysate, (2) Human brain lysate using GRIA1 (phospho S845) monoclonal antibody, clone GFH-7.

Gene Summary:
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq