MEF2A/MEF2C monoclonal antibody, clone ABGA-13
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More Files
- More Functions
Western Blot (Cell lysate)
Western Blot analysis of Raji cell lysate with MEF2A/MEF2C monoclonal antibody, clone ABGA-13 (Cat # MAB20474).
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic peptide of human MEF2A/MEF2C.
Immunogen
A synthetic peptide corresponding to human MEF2A/MEF2C.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Flow Cytometry (1:30)
Immunocytochemistry (1:50-1:200)
Immunofluorescence (1:50-1:200)
Immunohistochemistry (1:50-1:200)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot analysis of Raji cell lysate with MEF2A/MEF2C monoclonal antibody, clone ABGA-13 (Cat # MAB20474).Immunohistochemistry
Immunocytochemistry
Immunofluorescence
Flow Cytometry
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Gene Info — MEF2A
Entrez GeneID
4205Protein Accession#
Q02078;Q06413Gene Name
MEF2A
Gene Alias
ADCAD1, RSRFC4, RSRFC9
Gene Description
myocyte enhancer factor 2A
Gene Ontology
HyperlinkGene Summary
The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression. The myogenic basic helix-loop-helix proteins, including myoD (MIM 159970), myogenin (MIM 159980), MYF5 (MIM 159990), and MRF4 (MIM 159991) are one class of identified factors. A second family of DNA binding regulatory proteins is the myocyte-specific enhancer factor-2 (MEF2) family. Each of these proteins binds to the MEF2 target DNA sequence present in the regulatory regions of many, if not all, muscle-specific genes. The MEF2 genes are members of the MADS gene family (named for the yeast mating type-specific transcription factor MCM1, the plant homeotic genes 'agamous' and 'deficiens' and the human serum response factor SRF (MIM 600589)), a family that also includes several homeotic genes and other transcription factors, all of which share a conserved DNA-binding domain.[supplied by OMIM
Other Designations
MADS box transcription enhancer factor 2, polypeptide A (myocyte enhancer factor 2A)
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Gene Info — MEF2C
Entrez GeneID
4208Protein Accession#
Q02078;Q06413Gene Name
MEF2C
Gene Alias
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Gene Description
myocyte enhancer factor 2C
Omim ID
600662Gene Ontology
HyperlinkGene Summary
polypeptide C (myocyte enhancer factor 2C)
Other Designations
MADS box transcription enhancer factor 2, polypeptide C (myocyte enhancer factor 2C)
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Interactome
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Pathway
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Disease
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