LBR monoclonal antibody, clone EDO-12
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic peptide of human LBR.
Immunogen
A synthetic peptide corresponding to human LBR.
Host
Rabbit
Theoretical MW (kDa)
70.703
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunocytochemistry (1:100-1:500)
Immunofluorescence (1:100-1:500)
Immunohistochemistry (1:50-1:200)
Immunoprecipitation (1:30)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot analysis of Jurkat cell lysate with LBR monoclonal antibody, clone EDO-12 (Cat # MAB20437).Immunohistochemistry
Immunocytochemistry
Immunofluorescence
Immunoprecipitation
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Gene Info — LBR
Entrez GeneID
3930Protein Accession#
Q14739Gene Name
LBR
Gene Alias
DHCR14B, FLJ43126, LMN2R, MGC9041, PHA
Gene Description
lamin B receptor
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the ERG4/ERG24 family. It localized in the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified. [provided by RefSeq
Other Designations
OTTHUMP00000035631|integral nuclear envelope inner membrane protein
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Interactome
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Disease
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