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LAMA3/LAMA5 monoclonal antibody, clone AOAB-12 

  • Catalog # : MAB20435
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against synthetic peptide of human LAMA3/LAMA5.
  • Immunogen:
  • A synthetic peptide corresponding to human LAMA3/LAMA5.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 366.649
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Immunocytochemistry (1:50-1:200)
    Immunofluorescence (1:50-1:200)
    Western Blot (1:500-1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
  • Storage Instruction:
  • Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western Blot analysis of HeLa cell lysate with LAMA3/LAMA5 monoclonal antibody, clone AOAB-12 (Cat # MAB20435).
  • Immunocytochemistry
  • Immunofluorescence
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunocytochemistry
  • Immunofluorescence
  • Gene Information
  • Entrez GeneID:
  • 3909
  • Gene Name:
  • LAMA3
  • Gene Alias:
  • BM600,E170,LAMNA,LOCS,lama3a
  • Gene Description:
  • laminin, alpha 3
  • Gene Summary:
  • Laminins are basement membrane components thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. The protein encoded by this gene is the alpha-3 subunit of laminin 5, which is a complex glycoprotein composed of three subunits (alpha, beta, and gamma). Laminin 5 is thought to be involved in cell adhesion, signal transduction and differentiation of keratinocytes. Mutations in this gene have been identified as the cause of Herlitz type junctional epidermolysis bullosa. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq
  • Other Designations:
  • BM600 150kD subunit,epiligrin 170 kda subunit,epiligrin alpha 3 subunit,kalinin 165kD subunit,laminin alpha 3 subunit,laminin, alpha 3 (nicein (150kD), kalinin (165kD), BM600 (150kD), epilegrin),laminin-5 alpha 3 chain,nicein 150kD subunit
  • Gene Information
  • Entrez GeneID:
  • 3911
  • Gene Name:
  • LAMA5
  • Gene Alias:
  • KIAA1907
  • Gene Description:
  • laminin, alpha 5
  • Gene Summary:
  • Components of the extracellular matrix exert myriad effects on tissues throughout the body. In particular, the laminins, a family of heterotrimeric extracellular glycoproteins, affect tissue development and integrity in such diverse organs as the kidney, lung, skin, and nervous system. It is thought that laminins mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Laminins function as heterotrimeric complexes of alpha, beta, and gamma chains, with each chain type representing a different subfamily of proteins. The protein encoded by this gene belongs to the alpha subfamily of laminin chains and is a major component of basement membranes. Two transcript variants encoding different isoforms have been found for this gene, but the full-length nature of one of them has not been determined. [provided by RefSeq
  • Other Designations:
  • laminin alpha 5,laminin alpha-5 chain
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