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Last updated: 2021/8/8

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L1CAM monoclonal antibody, clone AAFD-12 

  • Catalog # : MAB20432
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against synthetic peptide of human L1CAM.
  • Immunogen:
  • A synthetic peptide corresponding to human L1CAM.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 140.003
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Immunohistochemistry (1:50-1:200)
    Western Blot (1:500-1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
  • Storage Instruction:
  • Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Immunohistochemistry
  • Application Image
  • Western Blot
  • Immunohistochemistry
  • Gene Information
  • Entrez GeneID:
  • 3897
  • Gene Name:
  • L1CAM
  • Gene Alias:
  • CAML1,CD171,HSAS,HSAS1,MASA,MIC5,N-CAML1,S10,SPG1
  • Gene Description:
  • L1 cell adhesion molecule
  • Gene Summary:
  • The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of a neuron-specific exon is thought to be functionally relevant. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000025992,antigen identified by monoclonal antibody R1,neural cell adhesion molecule L1
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