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Last updated: 2021/8/8

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HSPB8 monoclonal antibody, clone IOD-8 

  • Catalog # : MAB20352
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against synthetic peptide of human HSPB8.
  • Immunogen:
  • A synthetic peptide corresponding to human HSPB8.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 21.604
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Immunocytochemistry (1:50-1:100)
    Immunofluorescence (1:50-1:100)
    Immunohistochemistry (1:50-1:100)
    Western Blot (1:500-1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
  • Storage Instruction:
  • Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • Western Blot analysis of human fetal heart tissue lysate with HSPB8 monoclonal antibody, clone IOD-8 (Cat # MAB20352).
  • Immunohistochemistry
  • Immunocytochemistry
  • Immunofluorescence
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Immunohistochemistry
  • Immunocytochemistry
  • Immunofluorescence
  • Gene Information
  • Gene Name:
  • HSPB8
  • Gene Alias:
  • CMT2L,DHMN2,E2IG1,H11,HMN2,HMN2A,HSP22
  • Gene Description:
  • heat shock 22kDa protein 8
  • Gene Summary:
  • The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. [provided by RefSeq
  • Other Designations:
  • E2-induced gene 1,heat shock 27kDa protein 8,heat shock protein beta-8,protein kinase H11,small stress protein-like protein HSP22
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