PCSK9 monoclonal antibody, clone ABFB-16
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic peptide of human PCSK9.
Immunogen
A synthetic peptide corresponding to human PCSK9.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunoprecipitation (1:20)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Instruction
Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of HepG2 cell lysate with PCSK9 monoclonal antibody.Immunoprecipitation
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Gene Info — PCSK9
Entrez GeneID
255738Protein Accession#
Q8NBP7Gene Name
PCSK9
Gene Alias
FH3, HCHOLA3, LDLCQ1, NARC-1, NARC1
Gene Description
proprotein convertase subtilisin/kexin type 9
Gene Ontology
HyperlinkGene Summary
This gene encodes a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. The encoded protein is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum. The protein may function as a proprotein convertase. This protein plays a role in cholesterol homeostasis and may have a role in the differentiation of cortical neurons. Mutations in this gene have been associated with a third form of autosomal dominant familial hypercholesterolemia (HCHOLA3). [provided by RefSeq
Other Designations
OTTHUMP00000009833|convertase subtilisin/kexin type 9 preproprotein|neural apoptosis regulated convertase 1
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