HMBS monoclonal antibody, clone FEG-8
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More Files
- More Functions
Western Blot (Cell lysate)
Western Blot (Cell lysate) analysis of HepG2 cell lysate.
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic peptide of human HMBS.
Immunogen
A synthetic peptide corresponding to human HMBS.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Western Blot (1:500-2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot (Cell lysate) analysis of HepG2 cell lysate. -
Gene Info — HMBS
Entrez GeneID
3145Protein Accession#
P08397Gene Name
HMBS
Gene Alias
PBG-D, PBGD, UPS
Gene Description
hydroxymethylbilane synthase
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the hydroxymethylbilane synthase superfamily. The encoded protein is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. Mutations in this gene are associated with the autosomal dominant disease acute intermittent porphyria. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq
Other Designations
porphobilinogen deaminase|pre-uroporphyrinogen synthase|uroporphyrinogen I synthase|uroporphyrinogen I synthetase
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Interactome
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Pathway
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Disease
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