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Last updated: 2022/5/22

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HAMP monoclonal antibody, clone AAHH-8 

  • Catalog # : MAB20136
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against synthetic peptide of human HAMP.
  • Immunogen:
  • A synthetic peptide corresponding to human HAMP.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 9.408
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Western Blot (1:500-1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
  • Storage Instruction:
  • Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • Western Blot analysis of human plasma lysate with HAMP monoclonal antibody, clone AAHH-8 (Cat # MAB20136).
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Gene Information
  • Gene Name:
  • HAMP
  • Gene Alias:
  • HEPC,HEPCIDIN,HFE2B,LEAP-1,LEAP1,PLTR
  • Gene Description:
  • hepcidin antimicrobial peptide
  • Gene Summary:
  • The product encoded by this gene is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity. Mutations in this gene cause hemochromatosis type 2B, also known as juvenile hemochromatosis, a disease caused by severe iron overload that results in cardiomyopathy, cirrhosis, and endocrine failure. [provided by RefSeq
  • Other Designations:
  • liver-expressed antimicrobial peptide,putative liver tumor regressor
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