HAMP monoclonal antibody, clone AAHH-8
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More Files
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Western Blot (Tissue lysate)
Western Blot analysis of human plasma lysate with HAMP monoclonal antibody, clone AAHH-8 (Cat # MAB20136).
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic peptide of human HAMP.
Immunogen
A synthetic peptide corresponding to human HAMP.
Host
Rabbit
Theoretical MW (kDa)
9.408
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western Blot analysis of human plasma lysate with HAMP monoclonal antibody, clone AAHH-8 (Cat # MAB20136). -
Gene Info — HAMP
Entrez GeneID
57817Protein Accession#
P81172Gene Name
HAMP
Gene Alias
HEPC, HEPCIDIN, HFE2B, LEAP-1, LEAP1, PLTR
Gene Description
hepcidin antimicrobial peptide
Gene Ontology
HyperlinkGene Summary
The product encoded by this gene is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity. Mutations in this gene cause hemochromatosis type 2B, also known as juvenile hemochromatosis, a disease caused by severe iron overload that results in cardiomyopathy, cirrhosis, and endocrine failure. [provided by RefSeq
Other Designations
liver-expressed antimicrobial peptide|putative liver tumor regressor
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Interactome
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Disease
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