HBG1/HBG2 monoclonal antibody, clone AADB-8
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More Files
- More Functions
Western Blot (Cell lysate)
Western Blot analysis of K562 cell lysate with HBG1/HBG2 monoclonal antibody, clone AADB-8 (Cat # MAB20119).
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic peptide of human HBG1/HBG2.
Immunogen
A synthetic peptide corresponding to human HBG1/HBG2.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot analysis of K562 cell lysate with HBG1/HBG2 monoclonal antibody, clone AADB-8 (Cat # MAB20119). -
Gene Info — HBG1
Entrez GeneID
3047Protein Accession#
P69891;P69892Gene Name
HBG1
Gene Alias
HBGA, HBGR, HSGGL1, PRO2979
Gene Description
hemoglobin, gamma A
Omim ID
142200Gene Ontology
HyperlinkGene Summary
The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'. [provided by RefSeq
Other Designations
A-gamma globin|gamma A hemoglobin|gamma globin|hemoglobin gamma-a chain|hemoglobin, gamma, regulator of
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Gene Info — HBG2
Entrez GeneID
3048Protein Accession#
P69891;P69892Gene Name
HBG2
Gene Alias
FLJ76540
Gene Description
hemoglobin, gamma G
Omim ID
142250Gene Ontology
HyperlinkGene Summary
The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'- epsilon -- gamma-G -- gamma-A -- delta -- beta--3'. [provided by RefSeq
Other Designations
G-gamma globin|OTTHUMP00000069638|abnormal hemoglobin|hemoglobin gamma-G|methemoglobin
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Interactome
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Disease
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