NR3C1 monoclonal antibody, clone AOOE-14
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic peptide of human NR3C1.
Immunogen
A synthetic peptide corresponding to human NR3C1.
Host
Rabbit
Theoretical MW (kDa)
85.659
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Flow Cytometry (1:50)
Western Blot (1:1000-1:5000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot analysis of A431 cell lysate with NR3C1 monoclonal antibody, clone AOOE-14 (Cat # MAB20105).Flow Cytometry
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Gene Info — NR3C1
Entrez GeneID
2908Protein Accession#
P04150Gene Name
NR3C1
Gene Alias
GCCR, GCR, GR, GRL
Gene Description
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
Omim ID
138040Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a receptor for glucocorticoids that can act as both a transcription factor and as a regulator of other transcription factors. This protein can also be found in heteromeric cytoplasmic complexes along with heat shock factors and immunophilins. The protein is typically found in the cytoplasm until it binds a ligand, which induces transport into the nucleus. Mutations in this gene are a cause of glucocorticoid resistance, or cortisol, resistance. Alternate splicing, the use of at least three different promoters, and alternate translation initiation sites result in several transcript variants encoding the same protein or different isoforms, but the full-length nature of some variants has not been determined. [provided by RefSeq
Other Designations
nuclear receptor subfamily 3, group C, member 1
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Interactome
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Disease
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