GLS monoclonal antibody, clone FIA-7
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic peptide of human GLS.
Immunogen
A synthetic peptide corresponding to human GLS.
Host
Rabbit
Theoretical MW (kDa)
73.461
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunocytochemistry (1:50-1:200)
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry
Immunocytochemistry
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Gene Info — GLS
Entrez GeneID
2744Protein Accession#
O94925Gene Name
GLS
Gene Alias
AAD20, DKFZp686O15119, FLJ10358, GLS1, KIAA0838
Gene Description
glutaminase
Omim ID
138280Gene Ontology
HyperlinkGene Summary
Sahai (1983) [PubMed 6825316] demonstrated phosphate-activated glutaminase (EC 3.5.1.2) in human platelets. It is the major enzyme yielding glutamate from glutamine. Significance of the enzyme derives from its possible implication in behavior disturbances in which glutamate acts as a neurotransmitter (Prusiner, 1981). High heritability of platelet glutaminase was indicated by studies of Sahai and Vogel (1983) [PubMed 6682827] who found an intraclass correlation coefficient of 0.96 for monozygotic twins and 0.53 for dizygotic twins.[supplied by OMIM
Other Designations
K-glutaminase|L-glutamine amidohydrolase|glutaminase C|glutaminase, phosphate-activated
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Interactome
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Disease
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